THE 2-MINUTE RULE FOR ONOLIDINE

There's a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors during the dorsal horn to minimize afferent agony transmission and deliver analgesia. For that reason, medication like clonidine that concentrate on alpha-2 receptors can affect the transmission of pain.Relates to clonidine: oral p